Carbohydrate Kinases: A Conserved Mechanism Across Differing Folds
نویسندگان
چکیده
منابع مشابه
Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism.
The surface comparison of different serine-threonine and tyrosine kinases reveals a set of 30 residues whose spatial positions are highly conserved. The comparison between active and inactive conformations identified the residues whose positions are the most sensitive to activation. Based on these results, we propose a model of protein kinase activation. This model explains how the presence of ...
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ژورنال
عنوان ژورنال: Catalysts
سال: 2019
ISSN: 2073-4344
DOI: 10.3390/catal9010029